From form to function: New heights in kidney organoids.

Levinsohn, Jonathan; Susztak, Katalin · Cell Stem Cell · 2025

basic_science · Level V

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Abstract

In this issue of Cell Stem Cell, Huang et al.<sup>1</sup> address the challenge of creating organoids that more closely replicate kidney spatial patterning and function. They develop region-specific progenitor assembloids mimicking native architecture. After transplantation into mice, which further promotes differentiation, they demonstrate functional and disease modeling capability.

Medical subject headings