Rethinking Propagation Methods for Interactive Medical Image Segmentation.

Zhu, Shengqian; Shen, Yuncheng; Yin, Yingyong; Song, Ying; Yi, Zhang; Li, Guangjun; Hu, Junjie · IEEE J Biomed Health Inform · 2026

basic_science · Level V

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Abstract

Propagation-based methods have drawn increasing research attention in interactive medical image segmentation. However, existing propagation-based methods face two significant challenges: 1) Due tothe continuous nature of anatomical structures within the organs and tumors throughout the volume, over-propagation is likely to occur as the propagation process reaches the end of structures, leadingto a degradation in segmentation performance. 2) During the multi-round refinement process, selecting the worst-segmented slice for refinement tends to hinder the optimization of segmentation results. To overcome these challenges, we propose the Discrepancy Aware Network (DANet), which includes a Discrepancy Learning Module (DLM) and employs a confidence loss to achieve accurate segmentation. Specifically, DLM captures the temporal-contextual discrepancy between previous and current slices, enabling the model to perceive the variations of the target. Furthermore, the confidence loss is responsible for regularizing the over-confident segmentation at the image level by estimating the target foreground. Additionally, we design a straightforward slice selection strategy to optimize the refinement process. Extensive experimental results on five public medical datasets demonstrate significant improvements over state-of-the-art methods (e.g., with +1.07% improvement on the MSD-Spleen dataset).

Medical subject headings