Endogenous Electric Fields: A Natural Driver for Infrared-Activated Transparent Electronic Skin in Wound Healing.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41105476.
- Also identified by DOI 10.1021/acs.nanolett.5c04223.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A flexible, self-powered, and transparent electronic skin (e-skin) is constructed by combining endogenous electric field modulation and infrared thermal stimulation to accelerate wound healing. The e-skin comprises (1) a transparent conductive layer for real-time wound monitoring, fabricated by thermal deposition of hexadecyltrimethylammonium bromide (CTAB)-functionalized carbon nanotubes (C-MWCNTs) with polydimethylsiloxane (PDMS); (2) a photothermal interface using Pd@Au nanoframes for infrared therapy; and (3) self-powered electric fields mimicking bioelectric signals. Antibacterial assays of the e-skin showed >160% bacterial suppression at the peak output of 0.25-0.59 V and 90-140% suppression at the baseline output of 0.05-0.12 V. In vitro tests demonstrated 90% <i>E. coli</i> elimination within 10 min. In vivo studies on rabbits revealed a 50% reduction in healing time (7 days) via synergistic photothermal-electrical therapy. This e-skin offers a promising approach to advanced wound care.
Medical subject headings
- Wound Healing
- Wearable Electronic Devices