DiffuSETS: 12-Lead ECG generation conditioned on clinical text reports and patient-specific information.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41142907.
- Also identified by DOI 10.1016/j.patter.2025.101291 and PMC identifier 12546759.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The scarcity of high-quality electrocardiogram (ECG) data, driven by privacy concerns and limited medical resources, creates a pressing need for effective ECG signal generation. Existing approaches for generating ECG signals typically rely on small training datasets, lack comprehensive evaluation frameworks, and overlook potential applications beyond data augmentation. To address these challenges, we propose DiffuSETS, a framework capable of generating ECG signals with high semantic alignment and fidelity. DiffuSETS accepts various modalities of clinical text reports and patient-specific information as inputs, enabling the creation of clinically meaningful ECG signals. Additionally, we introduce a comprehensive benchmarking methodology to assess the effectiveness of ECG generative models. Our model achieves excellent results in tests, proving its superiority in the task of ECG generation. Furthermore, we showcase its potential to mitigate data scarcity while exploring applications in cardiology education and medical knowledge discovery.