A 62-Year-Old Woman with Diarrhea after Hematopoietic Stem-Cell Transplantation.

Suárez, Edwin U; Torres-Saavedra, Fabio; López-Lorenzo, José L; Pérez-Sáenz, María Á; Pardo-Gambarte, Laura; Solán-Blanco, Laura; Llamas, Pilar; Carias-Calix, Rafael et al. · NEJM Evid · 2025

case_report · Level V

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Abstract

Morning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry on this tradition by presenting a patient's chief concern and story, inviting the reader to develop a differential diagnosis and discover the diagnosis alongside the authors of the case. This report examines the story of a 62-year-old woman who presented with diarrhea and fatigue 8 weeks after haploidentical hematopoietic stem-cell transplantation. Using targeted questions, physical examination, and diagnostic testing, an illness script for the presentation emerges. As the clinical course progresses, the differential is refined until a final diagnosis is made.

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