Biomarkers in High-Grade Serous Ovarian Cancer: Context Is Everything.
editorial · Level V
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- Record sourced from PubMed, PMID 41166600.
- Also identified by DOI 10.1158/1078-0432.CCR-25-2851.
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Abstract
The Oxford Classic Epithelial-to-Mesenchymal Transition (OxC-EMT) score identifies a high-risk subgroup of patients with high-grade serous carcinoma with inferior survival. This commentary discusses the evaluation of high-grade serous carcinoma biomarkers in context and the important steps in transition from a prognostic to a validated predictive biomarker to inform clinical utility. See related article by Rai et al., p. 188.
Medical subject headings
- Biomarkers, Tumor
- Ovarian Neoplasms
- Cystadenocarcinoma, Serous