Heart failure diagnosis: Impacts of atrial fibrillation on the diagnostic marker NT-proBNP.

Chen, Yang; McDowell, Garry; Lip, Gregory Y H · PLoS Med · 2025

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Abstract

A recent PLOS Medicine study shows that atrial fibrillation lowers the specificity of the biomarker NT-proBNP for heart failure. Adjusted thresholds and better echocardiography access are therefore required for NT-proBNP to remain as a high negative predictive value rule-out test in primary care.

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