Cellular profiling identifies targetable T cell phenotypes in lymphocytic variant hypereosinophilic syndrome.

Tefft, Kristy; Wang, Amy; Reinstein, Zachary Z; Zhang, Yue; Pillai, Arundhati; Hwang, Sunghee; Ng, Spencer; Cho, Raymond J et al. · J Clin Invest · 2025

case_series · Level IV

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Abstract

With cell-by-cell mapping, we charted immune cells in lymphocytic-variant hypereosinophilic syndrome, found drug targets, and showed targeted therapy removed disease-causing cells and eased symptoms.

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