When more is not worse: Genetic subtypes of obesity challenge conventional risk paradigms.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 41192358.
- Also identified by DOI 10.1016/j.cmet.2025.10.002.
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Abstract
Emerging evidence challenges the view of obesity as a uniform metabolic risk. Spotlighting the recent Nature Medicine study by Chami et al.,<sup>1</sup> this piece discusses how "uncoupling" adiposity from its cardiometabolic consequences reveals biologically distinct subtypes of obesity. Integrating imaging and multi-omics offers a promising path toward personalized obesity management and deeper mechanistic insight.
Medical subject headings
- Obesity