GBA Solver: a user-friendly web server for growth balance analysis.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 41206759.
- Also identified by DOI 10.1093/bioinformatics/btaf609 and PMC identifier 12638059.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
GBA Solver is a web-based application that enables efficient construction and numerical solution of coarse-grained growth balance analysis (GBA) models containing up to 20 reactions. The platform features an intuitive spreadsheet-based interface that eliminates the need for programming, integrates kinetic parameters from the BRENDA enzyme database, and provides interactive visualizations for model exploration. By lowering technical barriers, GBA Solver makes GBA modeling accessible to a wider scientific community, expanding the computational toolkit for investigating cell metabolism and growth. GBA Solver is freely available at: https://cellgrowthsim.com/. The source code is available at: https://doi.org/10.5281/zenodo.17250925.
Medical subject headings
- Software
- Computational Biology
- Models, Biological