Unlocking rejuvenating potential of mesenchymal progenitor cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41237757.
- Also identified by DOI 10.1016/j.cell.2025.10.011.
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Abstract
Age-dependent exhaustion of endogenous stem cell pools-and the resulting decline in tissue regeneration and homeostatic maintenance-is a hallmark of organismal aging and age-related pathology. In a study published in Cell, Liu and collaborators engineered human ESC-derived mesenchymal progenitor cells to give the ability to resist senescence, environmental stress, and malignant transformation.
Medical subject headings
- Mesenchymal Stem Cells
- Rejuvenation