Prospective Validation of the First US FDA-Approved Computer-Aided Quality Assessment Tool for Colonoscopy: An Initial Clinical Experience.

Brenner, Todd A; Labaki, Chris; Feuerstein, Joseph D; Berzin, Tyler M · Am J Gastroenterol · 2026

case_series · Level IV

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Abstract

We report a prospective pilot of GI Genius ColonPro 4.0 (Medtronic, Minneapolis, MN), the first US Food and Drug Administration-approved computer-aided quality (CAQ) platform for colonoscopy. ColonPro measurements of withdrawal time, cecal intubation, and Boston Bowel Preparation Score (BBPS) were compared with independent video review in 110 outpatient colonoscopies. Agreement between the CAQ and physicians was poor for BBPS (intraclass correlation coefficient = 0.40, P < 0.001) but strong for withdrawal time (intraclass correlation coefficient = 0.89, P < 0.001) and cecal intubation (κ = 0.79, P < 0.001). CAQ reliably measures withdrawal time and cecal intubation, but artificial intelligence-based BBPS scoring requires further validation before integration into current paradigms of colonoscopy quality.

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