From visualization to prediction: Dissecting metabolic heterogeneity with DDRTree.

Yu, Yonghua; Lin, Hong · Cell Rep Med · 2025

editorial · Level V

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Abstract

The discriminative dimensionality reduction tree (DDRTree) framework provides a powerful approach to unravel metabolic heterogeneity and delineate clinically relevant subtypes. In this issue, Qiu et al.<sup>1</sup> and Jia et al.<sup>2</sup> apply it to type 2 diabetes and obesity, identifying subtypes with distinct risk profiles.

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