18 F-FDG PET/CT Demonstrates Left Adrenal Neuroblastoma in a Pediatric Patient With Beckwith-Wiedemann Syndrome.

Zhou, Ziang; Wen, Xin; Xie, Peng; Yang, Jigang · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A 2-year-old girl with Beckwith-Wiedemann syndrome (BWS) underwent 18 F-FDG PET/CT for differential diagnosis of a left adrenal lesion. The imaging revealed moderate 18 F-FDG uptake in the left adrenal gland, accompanied by regional lymphadenopathy. Histopathologic examination confirmed the diagnosis of neuroblastoma. One year following multimodal therapy, follow-up 123 I-MIBG SPECT/CT did not demonstrate any abnormal MIBG accumulation. This case highlights the diagnostic and staging utility of 18 F-FDG PET/CT in pediatric BWS patients with neuroblastoma.

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