Exploring Prefrontal Cortex Involvement in Postural Control Across Degraded Sensory Conditions Using fNIRS and Classification.

Abstract

The prefrontal cortex (PFC) of the brain is involved in processing visual, vestibular, and somatosensory inputs to stabilise postural balance. However, the PFC's activation map for a standing person and different sensory inputs remains unclear. This study aimed to explore the PFC activity map and distinct haemodynamic responses during postural control when sensory inputs change. To this end, functional near-infrared spectroscopy (fNIRS) was employed to capture the haemodynamic responses throughout the PFC from a group of young adults standing in four sensory conditions. The results revealed distinct PFC activation patterns supporting sensory processing, motor planning, and cognitive control to maintain balance under different degraded sensory conditions. Furthermore, by applying machine learning classifiers and multivariate feature selection, the PFC locations and haemodynamic responses indicative of different sensory conditions were identified. The findings of this study offer valuable insights for optimising rehabilitation approaches, enhancing the design of fNIRS studies, and advancing brain-computer interface technologies for balance assessment and training.