Towards insulin independence in type 1 diabetes: Prospects for prevention and cure.

Sydney, Guy I; Perdigoto, Ana Luisa; Herold, Kevan C · PLoS Med · 2025

review · Level V

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Abstract

The discovery of insulin transformed type 1 diabetes from an acutely lethal illness to a chronic disease that is managed with insulin dependence. Now, exciting developments in preventive treatments and stem cell-based therapies bring the prospects of arresting the disease and achieving insulin independence for type 1 diabetics closer to reality.

Medical subject headings