High-grade 18 F-PSMA-1007 Uptake of Benign Prostatic Hyperplasia With Chronic Inflammation.
case_report · Level V
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- Record sourced from PubMed, PMID 41308110.
- Also identified by DOI 10.1097/RLU.0000000000006153.
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Abstract
Benign prostatic hyperplasia can show low-grade PSMA uptake, but rarely shows high-grade PSMA uptake. We describe 18 F-PSMA-1007 PET/CT and PET/MRI findings in a case of large benign prostatic hyperplasia with chronic inflammatory infiltrates and a high level of serum total prostate-specific antigen (32.6 ng/mL). The large benign prostatic hyperplasia of the transition zone showed heterogeneous signal intensity on the T2-weighted image and heterogeneous intense PSMA uptake with SUV max of 19. This case indicates that benign prostatic hyperplasia with chronic inflammation can show high-grade PSMA uptake mimicking or masking prostate cancer of the central gland.
Medical subject headings
- Prostatic Hyperplasia
- Inflammation
- Niacinamide
- Oligopeptides