Clinical Translation of Antibody Positron Emission Tomography for Cancer Imaging.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 41329470.
- Also identified by DOI 10.1158/1078-0432.CCR-25-3784.
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Abstract
Hepatocellular carcinoma (HCC) lacks precise and noninvasive diagnostic tools. To address this, a new positron emission tomography (PET) radiotracer, [68Ga]Ga-XH-06, was developed. It uses an antibody fragment to target glypican-3 (GPC3), a highly specific biomarker, successfully visualizing GPC3 expressions in patients with HCC, potentially meeting an important unmet need. See related article by Lin et al., p. 550.
Medical subject headings
- Positron-Emission Tomography
- Carcinoma, Hepatocellular
- Liver Neoplasms
- Glypicans
- Radiopharmaceuticals
- Neoplasms