COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of biomolecular complexes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41335450.
- Also identified by DOI 10.1093/bioinformatics/btaf606 and PMC identifier 12684709.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein-protein and protein-nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations. COCOMAPS 2.0 is accessible as a public web tool at https://aocdweb.com/BioTools/cocomaps2 and as a standalone code at https://doi.org/10.5281/zenodo.17390665.
Medical subject headings
- Software
- Proteins
- Nucleic Acids