Lung infection in orally inoculated SARS-CoV-2 hamsters.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41343436.
- Also identified by DOI 10.1371/journal.pone.0337915 and PMC identifier 12677567.
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Abstract
The digestive tropism of SARS-CoV-2 due to the presence of the same ACE2 receptor in the digestive system as in the respiratory system raised the question of the role of fecal-oral transmission in the pandemic. The aim of this study was to explore oral infection in hamsters model. SARS-CoV-2 inoculation via the oral and intranasal routes resulted in comparable infection in hamsters. In addition to implications for human health, oral infection could have implications for potential animal reservoirs.
Medical subject headings
- SARS-CoV-2
- COVID-19
- Lung