Visual and Quantitative Analysis of 123 I-Ioflupane SPECT Reveals Asymmetric Neuronal Degeneration in Fahr's Disease.
case_report · Level V
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- Record sourced from PubMed, PMID 41363943.
- Also identified by DOI 10.1097/RLU.0000000000006243.
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Abstract
Fahr's disease is a rare disorder characterized by bilateral and symmetric calcifications in brain structures, including the basal ganglia, cerebellum, thalamus, and cerebral white matter. The findings of 123 I-Ioflupane SPECT in Fahr's disease have only been reported in a limited number of case reports. We present the case of a 64-year-old woman with Fahr's disease who had reduced uptake in the striatum on both visual and quantitative assessment of 123 I-Ioflupane SPECT images. The striatal involvement was asymmetric, despite the presence of substantially symmetric calcifications on CT and MRI.
Medical subject headings
- Tomography, Emission-Computed, Single-Photon
- Nortropanes
- Neurodegenerative Diseases
- Basal Ganglia Diseases
- Calcinosis
- Nerve Degeneration