Vaccines to prevent bacterial sexually transmitted infections: Promise, progress, and public health potential.

Gottlieb, Sami L; Rees, Helen; Peters, Remco P H · PLoS Med · 2025

review · Level V

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Abstract

Asymptomatic transmission, inequitable access to diagnostics, and rising antimicrobial resistance are major barriers to controlling the bacterial sexually transmitted infections (STIs) gonorrhea, chlamydia, and syphilis. Developing vaccines against these infections has therefore become a key STI research priority, requiring innovative research, expedited clinical development, and increased investment.

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