Are ultrasensitive ctDNA assays ready for clinical use in early-stage NSCLC?

Khan, Sam; Li, Janice J N; Leighl, Natasha B · Cell · 2025

editorial · Level V

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Abstract

Disease recurrence in early-stage non-small cell lung cancer (NSCLC) remains a persistent clinical challenge, underscoring the need for better prognostic biomarkers. In this preview, we highlight the clinical implications of ultrasensitive ctDNA monitoring in lung cancer risk modeling reported by Black et al. in this issue of Cell.

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