Beyond Menopause: Ending the Inequality-Why Men with Prostate Cancer Still Lack Therapies for Hot Flushes.

Pedrani, Martino; Gillessen, Silke; Briers, Erik; Blanchard, Pierre; Joshua, Anthony M; Tombal, Bertrand · Eur Urol · 2026

expert_opinion · Level V

Where this comes from

Abstract

Androgen deprivation therapy (ADT) causes hot flushes that can disrupt an individual's quality of life. NK3R antagonists provide rapid, sustained, and nonhormonal relief of hot flushes in women, but an approved treatment is lacking for men. Pragmatic trials are needed to generate evidence to support approval of these agents for the ADT setting.

Medical subject headings