CRISPR quality control on a chip.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41393513.
- Also identified by DOI 10.1038/s44222-024-00159-4 and PMC identifier 12700641.
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Abstract
Combining the precision of CRISPR's DNA searching ability with the speed and scalability of electronics, we have developed an 'electronic DNA search engine', called a CRISPR-Chip, which not only enables DNA detection without amplification, but also showcases the untapped potential of merging molecular biology with nanomaterial electronics. Here, we discuss highlights and challenges on the journey from the initial idea to the commercialization of the CRISPR-Chip.