Intradural Spinal Malignant Peripheral Nerve Sheath Tumor on 18F-FDG PET/CT.

Huang, Hexiao; Tang, Pan; Tian, Rong; Wang, Hongxi · Clin Nucl Med · 2025

case_report · Level V

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Abstract

We present the FDG PET/CT findings of an intradural spinal malignant peripheral nerve sheath tumor (MPNST) in a 34-year-old woman with a 9-month history of progressive lower limb weakness and ascending sensory loss. Initial contrast-enhanced spinal MRI suggested infectious myelitis. However, 18F-FDG PET/CT revealed intense, linear FDG uptake along the cervicothoracic and upper lumbar spine (SUVmax 27.95), raising concern for a malignant process. Subsequent histopathologic analysis confirmed the diagnosis of MPNST.