Detection of Community Transmission of Clade Ib Mpox Virus in the United States.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 41405957.
- Also identified by DOI 10.1056/EVIDpha2500319.
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Abstract
AbstractA clade Ib mpox virus (MPXV) outbreak in Central and Eastern Africa has led to multiple travel-associated infections. In October 2025, clade Ib MPXV infection was confirmed in three unvaccinated, hospitalized men in California reporting no international travel. Phylogenetic analysis revealed clustering of these three MPXV infections with one recent travel-associated MPXV infection. This report provides evidence for local transmission of clade Ib MPXV in the Americas, occurring among gay, bisexual, and other men who have sex with men and their social networks.
Medical subject headings
- Mpox, Monkeypox