Intense 68 Ga-PSMA-11 Uptake of Perihilar Cholangiocarcinoma.

Man, Xiaojun; Dong, Changming; Dong, Aisheng; Song, Xiandong · Clin Nucl Med · 2026

case_report · Level V

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Abstract

An immunohistochemical study demonstrates that most of the cholangiocarcinomas have PSMA expression in the tumor neovasculature. PSMA PET findings of cholangiocarcinomas are rarely reported. We describe 68 Ga-PSMA-11 PET/CT and delayed abdominal 68 Ga-PSMA-11 PET/MRI findings in a case of mass-forming type of perihilar cholangiocarcinoma. The tumor showed intense PSMA uptake with SUV max of 10.8 on 68 Ga-PSMA-11 PET/CT and SUV max of 7.8 on delayed 68 Ga-PSMA-11 PET/MRI.

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