Update on antiobesity pharmacotherapy in adults: Current and emerging options.

Ziyadeh, Farah; Saliba, Sara; Bacha, Dania Salih; Mauer, Yael; Griebeler, Marcio L; Burguera, Bartolome · Cleve Clin J Med · 2026

review · Level V

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Abstract

Obesity is a chronic disease that increases the risk of developing other serious health conditions. Pharmacotherapy can help patients effectively manage obesity by achieving a healthier weight, but each antiobesity medication has its own benefits and risks that must be evaluated for each patient. This article reviews the available antiobesity medications, including the incretin mimetics, and emerging antiobesity medications currently under investigation.

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