Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?

Timberlake, Dylan T; Boppana, Sushmitha; Fernandez, James · Cleve Clin J Med · 2026

review · Level V

Where this comes from

Abstract

Because reactions to intravenous infusions of radiocontrast media, monoclonal antibodies, or chemotherapy agents can be severe and life-threatening, researchers have tried to decrease their rate and severity by giving antihistamines, corticosteroids, or both before the infusions. This review summarizes the information about corticosteroid pretreatment to prevent infusion-related reactions, to help clinicians determine which patients may benefit from it.

Medical subject headings