Capturing gene-cell duality in a cat's cradle.

Laddach, Anna; Progatzky, Fränze; Pachnis, Vassilis; Shapiro, Michael · Bioinformatics · 2026

basic_science · Level V

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Abstract

CatsCradle is an R package for single-cell analysis that exploits the duality between cells and the genes they express. Our package provides tools to cluster genes, visualize relationships between them, and to explore relationships between gene clusters (programmes) and cell clusters (cell types). CatsCradle is available freely as an R Bioconductor package (https://bioconductor.org/packages/CatsCradle) and interfaces directly with Seurat (Hao et al. 2024) and SingleCellExperiment (Amezquita et al. 2020) data structures.

Medical subject headings