Lipid balance and chemoresistance in cancer cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 41521896.
- Also identified by DOI 10.7554/eLife.110231 and PMC identifier 12795500.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A shift in the balance between two lipids - cholesterol and sphingomyelin - makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.
Medical subject headings
- Drug Resistance, Neoplasm
- Cholesterol
- Sphingomyelins
- Lipid Metabolism
- Antineoplastic Agents
- Neoplasms