Detection of clonal hematopoiesis of indeterminate potential via genome or exome sequencing underestimates disease associations.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41528807.
- Also identified by DOI 10.1172/JCI198861 and PMC identifier 12948416.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Epidemiology studies underestimate the strength of the association between clonal hematopoiesis and disease due to false negatives from shallow, whole-genome sequencing versus deep targeted sequencing.
Medical subject headings
- Clonal Hematopoiesis
- Whole Genome Sequencing
- Exome Sequencing
- Genome, Human
- Exome