Total Pancreatectomy and Islet Auto Transplantation in South Australia: A Preliminary Evaluation of a 10-Year Experience.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 41555675.
- Also identified by DOI 10.5694/mja2.70129.
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Abstract
Hereditary pancreatitis causes severe early-onset pain and hospitalisation. In 15 Australian patients undergoing total pancreatectomy and islet auto transplantation (TPIAT), we observed a marked reduction in hospital admissions, inpatient days and emergency visits, complete analgesic cessation by 24 months and durable insulin independence in nearly half of the patients. These findings highlight TPIAT's potential to improve quality of life and reduce healthcare burden. Our programme aims to build evidence to support public funding and ensure equitable access to this procedure.
Medical subject headings
- Islets of Langerhans Transplantation
- Pancreatectomy
- Pancreatitis, Chronic