Reconstruction of a Devastated Ureter: Multi-institutional Experience with Robotic Intracorporeal Ileal Ureter Replacement.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 41577584.
- Also identified by DOI 10.1016/j.eururo.2026.01.011.
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Abstract
To report our multi-institutional outcomes with robotic intracorporeal ileal ureter replacement (RIUR). We performed a retrospective review of patients who underwent RIUR at three institutions from April 2016 to June 2025. Surgical success was defined as the absence of flank pain and of ureteral obstruction on functional imaging and/or endoscopic evaluation, and freedom from operative intervention related to RIUR at ≥6-mo follow-up. Of 48 patients, 31 (64.6%) had unilateral and 17 (35.4%) had bilateral reconstruction. Twenty (41.7%) had a history of radiation. Median stricture length was 20 cm (interquartile range [IQR] 20-25). In 19 patients (39.6%), a concomitant abdominopelvic reconstruction was performed (9 bladder augmentations, 5 contralateral ureteral reconstructions, and 5 other procedures). Median operative time was 359 min (IQR 292-418), estimated blood loss was 100 ml (IQR 50-175), and length of stay was 5 d (IQR 4-7). There were nine (18.8%) major (Clavien grade ≥III) 30-d complications: five urinary anastomotic leaks, two intra-abdominal abscesses, one small bowel leak that required exploratory laparotomy, and one renal bleed requiring angioembolization. Thirty-six patients (75%) had ≥6-mo follow-up, which confirmed surgical success in 33/36 (91.7%) at median follow-up of 24 mo (IQR 14-35). All three failures were in the radiation subgroup, which had a significantly lower rate of surgical success (76.9% vs 100%; p = 0.031). RIUR is an effective and durable treatment for patients with devastating ureteral injuries. However, the procedure is challenging and associated with a significant major complication rate. This study looked at a complex surgery in which a piece of intestine is used to rebuild the urinary tube that drains urine from the kidney to the bladder. Across three hospitals, the procedure worked well for the large majority of patients, and helped to restore function and relieve symptoms.