DNAvi: integration, statistics, and visualization of cell-free DNA fragment traces.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 41609423.
- Also identified by DOI 10.1093/bioinformatics/btag041 and PMC identifier 12904835.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
DNAvi is a Python-based tool for rapid grouped analysis and visualization of cell-free DNA fragment size profiles directly from electrophoresis data, overcoming the need for sequencing in basic fragmentomic screenings. It enables normalization, statistical comparison, and publication-ready plotting of multiple samples, supporting quality control and exploratory fragmentomics in clinical and research workflows. DNAvi is implemented in Python and freely available on GitHub at https://github.com/anjahess/DNAvi under a GNU General Public License v3.0, along with source code, documentation, and examples. An archived version is available under https://doi.org/10.5281/zenodo.18401705.
Medical subject headings
- Software
- Cell-Free Nucleic Acids
- Sequence Analysis, DNA
- DNA