Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis.

Ciullo, Alessandra; Jones, Xaviar M; Komuro, Hiroaki; Li, Liang; Nguyen, Anh; Marbán, Eduardo; Gamal-Eldin Ibrahim, Ahmed · JCI Insight · 2026

basic_science · Level V

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Abstract

TY2 is a drug based on a natural compound with potent anti-inflammatory effects. TY2 improved outcomes in mice with severe bacterial infection.

Medical subject headings