Back to basics: Bile acids in fat absorption.

Kuipers, Folkert; Verkade, Henkjan J; Freark de Boer, Jan · Cell Metab · 2026

basic_science · Level V

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Abstract

Using innovative methods to modify bile acid pool size and composition in mice, Chan et al. delineate that the "classical" function of bile acids, the body's endogenous soaps, in mediating intestinal fat absorption involves a delicate interplay between bile acid and fatty acid structures, with important metabolic implications.

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