Incremental Diagnostic Value of 68 Ga-FAPI PET/CT in Evaluating Pediatric Neuroblastoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 41650164.
- Also identified by DOI 10.1097/RLU.0000000000006356.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Neuroblastoma staging typically involves 18 F-FDG PET/CT or 123 I-MIBG scintigraphy, although their sensitivity may be limited. We present a 16-year-old girl with previously operated neuroblastoma who was reevaluated for recurrence. 18 F-FDG PET/CT showed minimal uptake in the abdominal lesion, slightly lower than liver activity, a hypodense hepatic lesion without FDG uptake initially considered benign, and no osseous involvement. In contrast, 68 Ga-FAPI PET/CT demonstrated heterogeneous moderate-to-intense uptake in the abdominal tumor, revealing additional hepatic and osseous metastases, which enabled accurate restaging and influenced management. This case highlights the incremental diagnostic value of FAPI PET/CT when FDG PET/CT underestimates disease extent.
Medical subject headings
- Positron Emission Tomography Computed Tomography
- Neuroblastoma