Nurturing eggs with hiPSC-derived cells to improve outcomes in in vitro fertilization.

Fang, Fang; Reijo Pera, Renee A · Cell Stem Cell · 2026

basic_science · Level V

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Abstract

Clinical success of in vitro maturation (IVM) for fertility treatment is currently limited by the lack of a reliable source of ovarian support cells (OSCs) to nurture oocytes. Kramme et al. develop "Fertilo," a scalable, clinical-grade hiPSC-derived OSC product that significantly enhances oocyte maturation and improves clinical reproductive outcomes.<sup>1</sup>.

Medical subject headings