AAVLINK breaks the cargo barrier.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 41650939.
- Also identified by DOI 10.1016/j.cell.2026.01.005.
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Abstract
In this issue of Cell, Lin et al. present a new adeno-associated virus (AAV)-based toolbox that enables efficient expression of full-length proteins exceeding the conventional single-vector packaging limit. This technology overcomes key limitations of existing dual AAV vector strategies and broadens the applicability of AAV-mediated gene replacement and gene editing strategies to a wider range of genetic disorders.
Medical subject headings
- Dependovirus
- Genetic Vectors