Glucose as a Biomarker for Stress in Firefighters.

Stratton, Micah; Stoddard, Gregory J; Monje, Kahlil; Nygard, Lily; Yin, Jiahe; Feairheller, Deborah L; Phillips, Andy; Thiese, Matthew S · J Occup Environ Med · 2026

prospective_cohort · Level II

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Abstract

This study aims to assess glucose as a biomarker for the sympathetic stress response in firefighters. Fifteen professional firefighters wore continuous glucometers over a 12-day period. We observed glucose levels during on-duty emergency calls and off-duty stressful events. Perceived stress levels were reported, and metabolic confounders (food and drink intake) were recorded. Glucose both increased and decreased during stressful events, with 39% of on-duty glucose decreases being associated with physically demanding tasks. The magnitude of glucose change was affected by perceived stress and duration of emergency calls. Stressful events happened 5.43 times (95% CI, 4.31-6.85) more often on-duty. On-duty fasting glucose values varied significantly from off-duty fasting glucose values. Our findings shed light on the relationship between occupational stress and high prevalence of stress-related health conditions in firefighters.

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