Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption.

Laffin, Luke J; Nissen, Steven E · PLoS Med · 2026

review · Level V

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Abstract

Despite many antihypertensive options, uncontrolled hypertension remains pervasive. Aldosterone synthase inhibitors show robust blood pressure reductions and have the potential to reshape hypertension treatment, though cost and access may impact broad adoption.

Medical subject headings