Persistent PSMA Expression at a Subdural Hematoma Following Middle Meningeal Artery Embolization.
case_report · Level V
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- Record sourced from PubMed, PMID 41678782.
- Also identified by DOI 10.1097/RLU.0000000000006344.
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Abstract
An 82-year-old man on active surveillance for low-risk prostate cancer underwent 18 F-DCFPyL PET/CT PET/CT for rising PSA. Imaging revealed interval progression of known intraprostatic malignancy. Interestingly, intracranial uptake was seen along the right frontoparietal convexity, corresponding to a known chronic subdural hematoma (cSDH) in this patient who had previously undergone middle meningeal artery embolization. This case highlights prostate-specific membrane antigen (PSMA) expression associated with cSDH, likely reflecting inflammation-driven neoangiogenesis. Recognition of such uptake is essential to avoid misinterpretation as metastatic disease and may provide novel insights into cSDH pathophysiology and potential therapeutic targets.
Medical subject headings
- Meningeal Arteries
- Glutamate Carboxypeptidase II
- Embolization, Therapeutic
- Antigens, Surface
- Hematoma, Subdural