Radiation-Induced Side Effects to the Skin Due to 177 Lu-PSMA Extravasation : A Case Report.

Corveleyn, Heather; De Mey, Lynn; Raes, Laurens; Bracke, Amelientje; Bourgeois, Sophie · Clin Nucl Med · 2026

case_report · Level V

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Abstract

We report a case with clinical side effects related to extravasation of 177 Lu-PSMA (estimated activity of 2.25 GBq) after administration via the cubital vein. After initial cooling (±10 min), the patient was asked to elevate and mobilize the arm. Five weeks post-injection (p.i.), the patient reported localized pruritus. An erythematosqualous plaque with lichenification was observed. At 9 weeks p.i., a slight inflammatory hyperpigmentation remained; all other symptoms had disappeared.

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