Can generative artificial intelligence enhance evidence-based and personalized medicine?

Thirunavukarasu, Arun J · PLoS Med · 2026

review · Level V

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Abstract

Should clinical applications of generative artificial intelligence (GAI) be designed to follow treatment guidelines rigidly, provide individualized recommendations, or be somewhere in-between? A recent study in PLOS Medicine comparing GAI versus physician treatment recommendations highlights the importance of context- and patient-specific circumstances in decision-making.

Medical subject headings