Gastroduodenal Disorders.

Törnblom, Hans; Carbone, Florencia; Hasler, William L; Smout, André; Suzuki, Hidekazu; Tack, Jan; Talley, Nicholas J; Stanghellini, Vincenzo · Gastroenterology · 2026

review · Level V

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Abstract

Symptoms that can be attributed to the gastroduodenal area are classified into 5 categories: (1) functional dyspepsia, with 2 subcategories that can overlap: postprandial distress syndrome, with meal-induced symptoms of postprandial fullness or early satiation and epigastric pain syndrome, with epigastric pain or burning that does not occur exclusively postprandially; (2) nausea and vomiting disorders, which include 3 subcategories: chronic nausea vomiting syndrome; cyclic vomiting syndrome; and cannabinoid hyperemesis syndrome; (3) excessive belching disorders, defined as audible escapes of air from the esophagus or the stomach and classified into 2 subcategories depending on the origin of the refluxed gas: gastric or supragastric belching; (4) inability to belch syndrome, a new category defined by the self-reported inability to belch; and (5) rumination syndrome, defined by the repetitive, effortless regurgitation of recently ingested food into the mouth, followed by the reswallowing or expulsion of the food bolus.

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