Analysis of the efficacy of intense pulsed light combined with collagen wound dressings for treating facial postburn hyperpigmentation.

Abstract

Various treatments are available for postburn hyperpigmentation; however, the results are often disappointing. To evaluate the clinical efficacy and therapeutic value of intense pulsed light (IPL) combined with collagen wound dressings to treat facial postburn hyperpigmentation. Ninety patients with facial hyperpigmentation from second-degree burns were randomized to receive IPL plus collagen dressings or collagen dressings alone for 3 months. Evaluations were conducted using visual assessments, VISIA skin analysis, imaging software, and psychological scales. Of the 90 patients, 80 completed the study. The efficacy rate was 95.1 % in the experimental group versus 61.5 % in the control group (p < 0.05). Quantitative image analysis showed a significantly greater reduction in both the area and intensity (Average Optical Density) of hyperpigmentation in the experimental group compared to the control (p < 0.05). VISIA skin analysis confirmed superior improvement in spots, UV spots, and brown spots in the combination therapy group (p < 0.05). Furthermore, patients receiving combination therapy reported significantly greater satisfaction and showed more pronounced improvements in anxiety and depression scores (SAS and SDS, p < 0.05) than the control group. IPL combined with collagen wound dressings is effective and safe for treating facial postburn hyperpigmentation with minimal side effects. This treatment can also improve patients' psychological well-being and is recommended for clinical use.