Preventing Early Onset GBS Neonatal Sepsis - Are Second Line Intrapartum Antibiotics Equivalent to No Antibiotics at All?

Gray, Carrie; Khanal, Manisha; Narita, Michelle; Mott, Timothy · J Am Board Fam Med · 2025

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Abstract

Strongly encourage pregnant women with the history of a penicillin allergy to undergo prenatal allergy testing as first-line intrapartum antibiotic prophylaxis for group B strep (GBS) is superior to second-line or no antibiotics, which have similar rates of early onset sepsis (EOS).

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