Differences in Outcomes After Ileocecal Resection in Older Adults With Crohn's Disease in the Biologic Era.

Harris, Hailey M; Ghoneim, Sara; Kochar, Bharati; Casey, Kevin; Ananthakrishnan, Ashwin N · Am J Gastroenterol · 2026

retrospective_cohort · Level III

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Abstract

Older adults represent a growing proportion of patients with Crohn's disease (CD). We compared outcomes after ileocecal resection between older and younger patients with CD. We conducted a retrospective cohort study of patients who underwent ileocecal resection. Older adults were defined as those aged 60 years and older. Outcomes at one and five years were extracted from medical records. Among 86 older and 169 younger patients, older adults had lower odds of clinical recurrence at 1 year (OR 0.26) and 5 years (OR 0.40) but higher 5-year mortality (OR 20.55). Older adults had lower symptom-based clinical recurrence rates but higher mortality.